Every morning when I arrived in the workplace, women will examine the 960 cell parent embrionik in laboratory rats. After seven years, Lim Sai Kiang can finally see the results of research, the parent cells can effectively treat diabetes.
Lim, researchers from the Institute of Medical Biology Institute of Science, Technology and Research and partner, Associate Professor Li Guodong, have sought to isolate and develop cells that can produce pure insulin.
By do so, the researchers have created a slap in the control of blood sugar levels, in which diabetics can not afford their own because mencukupinya can not produce enough insulin to break sugar. Both believe that their research with mice can be applied to human cells pemroduksi to get the same pure insulin. The same optimism expressed by a professor from Harvard Medical School, which send a greeting to keep Lim.
"The working group of researchers is impressive. We need something to be placed on the body to treat patients with diabetes their condition, and this discovery gives us interesting things about the development of beta cells (which make insulin and issued), "said Professor Gordon Weir, Director of Clinical Islet Transplantation Program, which also holds approval at the Harvard Stem Cell Institute and the Joslin Diabetes Center in the United States (U.S.).
In their experiments, Lim and Li cells pemroduksi inject insulin to diabetic rats suffering and find that, in, from the level of blood sugar levels in the rat is back to normal. Tuesday is also able to survive until about three months. When a cell is taken, mouse blood sugar level back to the original.
Until now, research techniques that have not been able to create cells in the amount of insulin pemroduksi unlimited. Or cells that produced it is associated with tumors in rats called teratoma, which make use of the treatment is not suitable.
However, the Singapore team has been able to skim the hurdle with the master cells that have the same structure subseluler such as the beta cells are naturally found in the pancreas in the human digestive system.
"Maybe once mereplikasi modify the results of this technique in humans to help patients with diabetes, because many rats have the same characteristics with humans," said Lim.
One method that may be applied in medical treatment is to instill capsule full of cells that produce insulin under the skin, to control their development, and maintaining their immune cells attacked by the body.
"Now, patients with diabetes must inject insulin to last a lifetime and it is very painful for them, especially for those suffering from diabetes since a young age," says Li
Lim, researchers from the Institute of Medical Biology Institute of Science, Technology and Research and partner, Associate Professor Li Guodong, have sought to isolate and develop cells that can produce pure insulin.
By do so, the researchers have created a slap in the control of blood sugar levels, in which diabetics can not afford their own because mencukupinya can not produce enough insulin to break sugar. Both believe that their research with mice can be applied to human cells pemroduksi to get the same pure insulin. The same optimism expressed by a professor from Harvard Medical School, which send a greeting to keep Lim.
"The working group of researchers is impressive. We need something to be placed on the body to treat patients with diabetes their condition, and this discovery gives us interesting things about the development of beta cells (which make insulin and issued), "said Professor Gordon Weir, Director of Clinical Islet Transplantation Program, which also holds approval at the Harvard Stem Cell Institute and the Joslin Diabetes Center in the United States (U.S.).
In their experiments, Lim and Li cells pemroduksi inject insulin to diabetic rats suffering and find that, in, from the level of blood sugar levels in the rat is back to normal. Tuesday is also able to survive until about three months. When a cell is taken, mouse blood sugar level back to the original.
Until now, research techniques that have not been able to create cells in the amount of insulin pemroduksi unlimited. Or cells that produced it is associated with tumors in rats called teratoma, which make use of the treatment is not suitable.
However, the Singapore team has been able to skim the hurdle with the master cells that have the same structure subseluler such as the beta cells are naturally found in the pancreas in the human digestive system.
"Maybe once mereplikasi modify the results of this technique in humans to help patients with diabetes, because many rats have the same characteristics with humans," said Lim.
One method that may be applied in medical treatment is to instill capsule full of cells that produce insulin under the skin, to control their development, and maintaining their immune cells attacked by the body.
"Now, patients with diabetes must inject insulin to last a lifetime and it is very painful for them, especially for those suffering from diabetes since a young age," says Li
